JMC recently traveled with APHL and the eLEXNET management team to St. Petersburg, Florida to attend the 6th Manufactured Food Regulatory program Alliance (MFRPA) Meeting and the 3rd Governmental Food and Feed Laboratories Accreditation Meeting. The meeting is a potent reminder that FDA is committed to strengthening ties with food safety programs and laboratories at the local and State level. State food safety professionals are often the boots-on-the-ground response to a foodborne disease outbreak; they are also the first line of defense for the nation’s food supply. FDA therefore recognizes that the only way to realize its goal of an integrated food safety system is to work with State programs to standardize the methods, methodologies, processes, and capabilities of food safety systems nationwide. FDA’s Office of Partnerships (OP), the Office of Regulatory Affairs (ORA) and the Center for Food Safety and Nutrition (CFSAN) have released a series of Cooperative Agreements to implement best practices in regulatory agencies and help food and feed laboratories achieve ISO 17025 accreditation. These enhancements will ensure the integrity and accuracy of laboratory results, allowing FDA to truly partner with State programs on regulatory action. APHL and JMC are supporting this vision, identifying synergies across databases and exploring ways to make sharing data more efficient, both for States and at a national level. We are working with FDA’s Electronic Laboratory Network (eLEXNET) to make it easier for laboratories, epidemiologists, and regulatory officials to access, analyze, and proactively respond to possible threats to our nation’s food supply.